Proanthocyanidins are considered helpful in improving and preserving the elasticity of skin by stabilizing collagen and elastin. Pine Bark's anti-oxidant properties may be helpful in treating hypoxia from artereosclorosis, inflammation, and cardiac or cerebral infarction.

Pycnogencol (procyanidin extracted from Pinus maritima) is a trademarked, highly standardized extract of Pine Bark.